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Parkinson’s disease – one of the most frequent manifestations of hypoxic encephalopathy, usually develops after cardiac arrest. Acute postgipoksicheskaya Parkinson’s disease may appear during a coma caused by cardiac arrest, and persists for several hours. In this case, the intense spasms are generalized nature (myoclonic status) and can be triggered by touch, sound, aspiration of mucus from the upper respiratory tract, the introduction of a catheter, etc. Preservation of generalized myoclonic jerks in a few days usually indicates a lack of generic Eldepryl in the body.
Acute stage of Parkinson’s disease should be distinguished from the kinetic postgipoksicheskoy myoclonus (Lance syndrome – Adams), which often occurs after a respiratory arrest due to anesthesia failure, myocardial infarction, strangulation, severe attack of asthma. Postgipoksicheskaya kinetic myoclonia often appears at the output of the coma. Its characteristic feature is that it is triggered by motion, to a lesser extent – sensory stimuli. Because myoclonus involving facial muscles and throat, disturbed speech, swallowing. Walking becomes impossible because of frequent short-term shutdowns of muscle tone of the lower limbs and trunk (negative myoclonia), immediately arise when trying to build on their feet. As a result, patients are confined to a wheelchair.
Parkinson’s disease – a rare complication of neuroleptic treatment, including clozapine (late myoclonia), tricyclic antidepressants, serotoninomimeticheskimi drugs (trazodone, methylphenidate), levodopa therapy, Eldepryl, bismuth subsalicylate. In the application of lithium preparations described a condition resembling Creutzfeldt – Jakob disease, which manifests itself myoclonus, coarse tremors, cerebellar, extrapyramidal, and cognitive impairment, periodic outbreaks sharp waves on EEG, regressing after withdrawal of the drug. Myoclonia may also occur with the introduction of the drug propofol.
Generalized myoclonia also hold for subacute sclerosing panencephalitis. Eldepryl in combination with levodopa may alleviate the suffering of patients with neuroblastoma, or lung cancer (as a paraneoplastic syndrome).

Originally developed Parkinson’s disease, against which the emerging and fast growing signs of dementia – in these cases is difficult differential diagnosis of Parkinson’s disease. Parkinson’s disease and dementia develop in parallel.
Diagnostics simplifies BDTL with regular Eldepryl uses.
Identification of two other characteristic symptoms:
pronounced fluctuations in attention and mental activity (during the day or several days), sometimes with transient episodes of confusion, which sometimes is mistaken for transient ischemic attacks,
persistent visual hallucinations, sometimes accompanied by other psychotic disorders, such as delusions of persecution (which may be spontaneous, but sometimes provoked and generic Eldepryl means).
In addition, the diagnostic value are:
- Postural instability early development, with frequent falls,
- Orthostatic hypotension with syncope,
- Hypersensitivity to neuroleptics.
Even in the absence of overt signs of parkinsonism in patients with DBTL appointment of neuroleptics, usually to correct hallucinatory syndrome, is fraught with a sharp deterioration in the rapidly growing rigidity, akinesia, and confusion can lead to death.
Treatment. Approximately one third of patients and other drugs Selegiline antiparkinsonian means are ineffective, the rest they often have only a modest proportion of patients deystvie. Eldepryl 5mg no less effective than in Parkinson’s disease. Sometimes the dose of levodopa can not bring to the therapeutic because of the appearance of psychotic or autonomic disorders.